Graphite (App)
Graphite is a free, lightweight open source 2D graphics editor and animation tool that features a procedural, node-based compositor, in addition to traditional layer-based workflows.
Friction (App)
Friction is an open source motion graphics and vector animation tool that lets you create smooth and responsive animations for the web and for video.
Synfig Studio (App)
Synfig Studio is an open source 2D animation app that can be used to produce both vector-based cut-out animation and film-quality animation using bitmap artwork.
Posted in2D Art Resource Free Drawing App Open Source
Inkscape (App)
Inkscape is a free and open source vector art editor that uses Scalable Vector Graphics (SVG), allowing your artwork to be scaled to any size without losing quality.